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Metabolic Health
The Science Behind Juvenescence's Breakthrough Product: Metabolic Switch
Recent developments in aging biology have revealed a beneficial role for ketones in healthspan. Juvenescence and scientists at the Buck Institute have developed an exogenous ketone product that lets anyone achieve the benefits of ketosis.
September 30, 2020
Read MoreKetosis & Metabolism
β-hydroxybutyrate and its Metabolic Effects on Age-associated Pathology
Aging is a universal and irreversible process that renders individuals vulnerable to many diseases. Increased β-HB has been reported to prevent or improve symptoms of various age-associated diseases.
April 7, 2020
Read MoreKetosis & Metabolism
On the Metabolism of Exogenous Ketones in Humans
Traditionally, ketosis has been achieved by following a “ketogenic” diet, but an alternative way to increase blood D-β-hydroxybutyrate (D-βHB) concentrations is ketone drinks, which effectively raise blood ketone concentrations.
October 29, 2017
Read MoreKetosis & Metabolism
A Ketone Ester Drink Lowers Human Ghrelin and Appetite
The ketones D-β-hydroxybutyrate (D-βHB) and acetoacetate are elevated during prolonged fast-
ing or during a ketogenic diet. An exogenous ketone ester suppresses the appetite hormone ghrelin and lowers perceived hunger and desire to eat.
October 5, 2017
Read MoreKetosis & Metabolism
Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice
Ketogenic diets (KD) may have similar metabolic effects to dietary caloric restriction. A cyclic KD improves midlife survival and memory performance in aging mice, without affecting maximal lifespan.
September 4, 2017
Read MoreKetosis & Metabolism
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
Concentrations of endogenous metabolites affect
histone acetylation and thereby couple cellular metabolic status and transcriptional regulation. β-HB is an inhibitor of histone deacetylase (HDAC) and protects against oxidative stress.
January 10, 2013
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