The Science Ketosis & Metabolism

Ketosis & Metabolism

We know ketosis boosts the metabolism to add energy and promote weight loss. But ketosis, metabolism & aging are also connected. Read more.

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Metabolic Health

The Science Behind Juvenescence's Breakthrough Product: Metabolic Switch

Recent developments in aging biology have revealed a beneficial role for ketones in healthspan. Juvenescence and scientists at the Buck Institute have developed an exogenous ketone product that lets anyone achieve the benefits of ketosis.

September 30, 2020

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Ketosis & Metabolism

β-hydroxybutyrate and its Metabolic Effects on Age-associated Pathology

Aging is a universal and irreversible process that renders individuals vulnerable to many diseases. Increased β-HB has been reported to prevent or improve symptoms of various age-associated diseases.

April 7, 2020

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Ketosis & Metabolism

On the Metabolism of Exogenous Ketones in Humans

Traditionally, ketosis has been achieved by following a “ketogenic” diet, but an alternative way to increase blood D-β-hydroxybutyrate (D-βHB) concentrations is ketone drinks, which effectively raise blood ketone concentrations.

October 29, 2017

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Ketosis & Metabolism

A Ketone Ester Drink Lowers Human Ghrelin and Appetite

The ketones D-β-hydroxybutyrate (D-βHB) and acetoacetate are elevated during prolonged fast- ing or during a ketogenic diet. An exogenous ketone ester suppresses the appetite hormone ghrelin and lowers perceived hunger and desire to eat.

October 5, 2017

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Ketosis & Metabolism

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice

Ketogenic diets (KD) may have similar metabolic effects to dietary caloric restriction. A cyclic KD improves midlife survival and memory performance in aging mice, without affecting maximal lifespan.

September 4, 2017

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Ketosis & Metabolism

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Concentrations of endogenous metabolites affect histone acetylation and thereby couple cellular metabolic status and transcriptional regulation. β-HB is an inhibitor of histone deacetylase (HDAC) and protects against oxidative stress.

January 10, 2013

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