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Regeneration
Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure
Human liver disease is modeled in swine. Liver cells transplanted, forming ectopic livers that cured fatal disease.
September 11, 2020
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Development of Ectopic Livers by Hepatocyte Transplantation Into Swine Lymph Nodes
Transplanted swine liver cells are engrafted into the lymph nodes, proliferated, and form ectopic mini-livers.
August 18, 2020
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Engineering strategies for generating hypoimmunogenic cells with high clinical and commercial value
The engineering of allogeneic cells to be ‘hypoimmunogenic’, also referred to as ‘universal’, so that they evade a host's immune system would be transformative for regenerative medicine.
October 29, 2019
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Toward a unified theory of aging and regeneration
A unified model of aging and loss of regenerative potential is emerging that may ultimately be translated into new therapeutic approaches for establishing induced tissue regeneration and modulation of the embryo-onco phenotype of cancer.
August 27, 2019
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Host Lymphotoxin-β Receptor Signaling Is Crucial for Angiogenesis of Metanephric Tissue Transplanted into Lymphoid Sites
Unraveling some of the molecular signaling that appears to be crucial for engrafted kidney tissue to grow.
August 18, 2019
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Kidney‐in‐a‐lymph node: A novel organogenesis assay to model human renal development and test nephron progenitor cell...
Expands upon findings in mice that show human ectopic kidney tissues can be grown using the lymph node as a bioreactor.
July 2, 2019
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Clonal derivation of white and brown adipocyte progenitor cell lines from human pluripotent stem cells
Exploration of an alternative approach involving the identification of clonal self-renewing human embryonic progenitor (hEP) cell lines following partial hPS cell differentiation and selection of scalable clones.
January 7, 2019
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