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Aging Science

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Ketosis & Metabolism

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Concentrations of endogenous metabolites affect histone acetylation and thereby couple cellular metabolic status and transcriptional regulation. β-HB is an inhibitor of histone deacetylase (HDAC) and protects against oxidative stress.

January 10, 2013

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